Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers
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DOI: 10.1021/acs.jmedchem.7b00484
Abstract: IKKβ plays a central role in the canonical NF-kB pathway, which has been extensively characterized. The role of IKKα in the noncanonical NF-kB pathway, and indeed in the canonical pathway as a complex with IKKβ,… read more here.
Keywords: canonical pathway; inhibitory kappa; kappa kinase; pathway ... See more keywords