Procyanidin B2 inhibits the activation of hepatic stellate cells and angiogenesis via the Hedgehog pathway during liver fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14543
Abstract: Liver fibrosis is a wound‐healing process of liver featured by the over‐deposition of extracellular matrix (ECM) and angiogenesis. However, the effective treatment is lacking. Procyanidin B2 (PB2) is a flavonoid extract abundant in grape seeds… read more here.
Keywords: fibrosis; angiogenesis; liver fibrosis; activation hepatic ... See more keywords
Andrographolide inhibits the activation of NLRP3 inflammasome in patients with COPD
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DOI: 10.1183/13993003.congress-2018.pa5246
Abstract: Background: The activation of NLRP3 inflammasome is involved in the aggravated inflammatory response of COPD exacerbations. However, there is a lack of treatment options targeting this specific pathway while andrographolide is shown to benefit certain… read more here.
Keywords: activation nlrp3; copd; andrographolide inhibits; activation ... See more keywords
Dexamethasone inhibits activation of monocytes/macrophages in a milieu rich in 27-oxygenated cholesterol
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DOI: 10.1371/journal.pone.0189643
Abstract: Molecular mechanisms underlying the decreased number of macrophages and T cells in the arteries of cholesterol-fed-rabbits following dexamethasone administration are unknown. We investigated the possibility that dexamethasone could affect activation of monocytic cells induced by… read more here.
Keywords: monocytes macrophages; dexamethasone inhibits; dexamethasone; inhibits activation ... See more keywords