Gomisin N inhibits adipogenesis and prevents high-fat diet-induced obesity
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40345
Abstract: Gomisin N (GN) is a physiological lignan derived from Schisandra chinensis. In the present study, we investigated the inhibitory effects of GN on differentiation of 3T3-L1 preadipocytes and the anti-obesity effects of GN in high-fat… read more here.
Keywords: fat diet; gomisin inhibits; inhibits adipogenesis; high fat ... See more keywords
Protocatechuic Acid Enhances Osteogenesis, but Inhibits Adipogenesis in C3H10T1/2 and 3T3-L1 Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of medicinal food"
DOI: 10.1089/jmf.2016.3833
Abstract: Abnormal activation of adipogenesis in mesenchymal stem cells (MSCs) and preadipocyte cells is associated with human metabolic disorders, such as osteoporosis and obesity. This study investigated the biological effects of protocatechuic acid (PCA) on the… read more here.
Keywords: inhibits adipogenesis; protocatechuic acid; osteogenesis inhibits; enhances osteogenesis ... See more keywords
GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β‐catenin and ALK5/SMAD2/3 pathways
Sign Up to like & getrecommendations! Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13310
Abstract: GDF11 is a member of the TGF‐β superfamily that was recently implicated as potential “rejuvenating” factor, which can ameliorate metabolic disorders. The main objective of the presented study was to closely characterize the role of… read more here.
Keywords: adipogenesis improves; inhibits adipogenesis; mature adipocytes; gdf11 inhibits ... See more keywords
Germacrone inhibits adipogenesis and stimulates lipolysis via the AMP‐activated protein kinase signalling pathway in 3T3‐L1 preadipocytes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.12674
Abstract: In a previous study, we reported that Aster spathulifolius Maxim extract (ASE) inhibited lipid accumulation and adipocyte differentiation in 3T3‐L1 cells. Of the components in ASE, germacrone (GM) was identified as a potent bioactive constituent.… read more here.
Keywords: adipogenesis stimulates; inhibits adipogenesis; germacrone inhibits; lipolysis via ... See more keywords