Pentoxifylline inhibits angiogenesis via decreasing Dll4 and Notch1 expression in mouse proepicardial explant cultures
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.03.015
Abstract: Abstract Pentoxifylline (PTX), a non‐specific inhibitor of cAMP phosphodiesterases, is commonly used for treatment of peripheral vascular disorders although its direct action on endothelial cells is not well described. The aim of this study was… read more here.
Keywords: vegf; mouse proepicardial; expression; dll4 notch1 ... See more keywords
Targeting TRAF3IP2 inhibits angiogenesis in glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.893820
Abstract: Increased vascularization, also known as neoangiogenesis, plays a major role in many cancers, including glioblastoma multiforme (GBM), by contributing to their aggressive growth and metastasis. Although anti-angiogenic therapies provide some clinical improvement, they fail to… read more here.
Keywords: glioblastoma; traf3ip2 inhibits; inhibits angiogenesis; targeting traf3ip2 ... See more keywords
Andrographolide Inhibits Angiogenesis by Inhibiting the Mir-21-5p/TIMP3 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.19194
Abstract: Angiogenesis provides nutrients and oxygen to promote tumor growth and affords a channel that facilitates tumor cell entry into the circulation. Andrographolide (Andro) possess anti-tumor activity; however, its direct effect on angiogenesis still needs to… read more here.
Keywords: inhibiting mir; angiogenesis; andrographolide inhibits; angiogenesis inhibiting ... See more keywords