Neferine, a bisbenzylisoquinoline alkaloid of Nelumbo nucifera, inhibits glutamate release in rat cerebrocortical nerve terminals through 5-HT1A receptors.
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DOI: 10.1016/j.ejphar.2020.173589
Abstract: Neferine, a bisbenzylisoquinoline alkaloid present in Nelumbo nucifera, has been reported to exhibit neuroprotective effects. Because reduced glutamatergic transmission through inhibition of glutamate release has been proposed as a mechanism of neuroprotection, we investigated whether… read more here.
Keywords: inhibits glutamate; glutamate release; ht1a receptors; neferine bisbenzylisoquinoline ... See more keywords