Teneligliptin inhibits IL‐1β‐induced degradation of extracellular matrix in human chondrocytes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29662
Abstract: The mechanisms driving the pathologic progression of osteoarthritis (OA) have not yet to be fully elucidated. Excessive and irreversible breakdown of the extracellular matrix is the main hallmark of OA. Inhibitors of DPP‐4 have been… read more here.
Keywords: teneligliptin inhibits; extracellular matrix; human chondrocytes; inhibits induced ... See more keywords
Ephrin-B2 inhibits Aβ25-35-induced apoptosis by alleviating endoplasmic reticulum stress and promoting autophagy in HT22 cells
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DOI: 10.1016/j.neulet.2019.03.028
Abstract: Previous studies have shown that Erythropoietin-producing hepatocellular carcinoma receptor B2 (EphB2) inhibited Aβ-induced neuron apoptosis and improved cognition in AD mice, but the role of which ligand Ephrin B2 (Ephrin-B2, efnB2) is not clear. The… read more here.
Keywords: ht22; apoptosis; ht22 cells; stress ... See more keywords
Tormentic acid inhibits IL-1β-induced chondrocyte apoptosis by activating the PI3K/Akt signaling pathway.
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DOI: 10.3892/mmr.2018.8425
Abstract: Interleukin-1β (IL-1β) accelerates degradation of the cartilage matrix and induces apoptosis of chondrocytes. Tormentic acid (TA) is a triterpene isolated from the stem bark of the Vochysia divergens plant, which has been demonstrated to exert in vitro… read more here.
Keywords: akt; chondrocyte apoptosis; apoptosis; pi3k akt ... See more keywords