Megakaryocyte/platelet-derived TGF-β1 inhibits megakaryopoiesis in bone marrow by regulating thrombopoietin production in liver
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021005977
Abstract: Key Points Loss of Tgfb1 expression in MKs increases MK production in BM and TPO expression in the liver. Inhibition of TGF-β1 might increase MK generation in vivo and in vitro. read more here.
Keywords: tgf inhibits; megakaryocyte platelet; production; inhibits megakaryopoiesis ... See more keywords