Valproate inhibits mitochondrial bioenergetics and increases glycolysis in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68725-5
Abstract: The widely used mood stabilizer valproate (VPA) causes perturbation of energy metabolism, which is implicated in both the therapeutic mechanism of action of the drug as well as drug toxicity. To gain insight into these… read more here.
Keywords: mitochondrial bioenergetics; glycolysis; inhibits mitochondrial; increases glycolysis ... See more keywords
TMED10 inhibits mitochondrial damage and protects neurons in ischemic stroke via the JNK signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental animals"
DOI: 10.1538/expanim.22-0060
Abstract: Stroke, a type of acute cerebrovascular disease, is a global disease with high mortality. Neuronal ischemia and hypoxia are closely related to occurrence and development of cognitive impairment. Transmembrane p24 trafficking protein 10 (TMED10) as… read more here.
Keywords: mitochondrial damage; tmed10; tmed10 inhibits; inhibits mitochondrial ... See more keywords