γ-Tocotrienol inhibits oxidative phosphorylation and triggers apoptosis by inhibiting mitochondrial complex I subunit NDUFB8 and complex II subunit SDHB.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology"
DOI: 10.1016/j.tox.2019.01.018
Abstract: Tocotrienols (T3s) are a subgroup of vitamin E and they have been widely tested to inhibit cell growth in various tumor types. Previous studies have shown that T3s inhibit cancer cell growth by targeting multiple… read more here.
Keywords: sdhb; inhibits oxidative; subunit complex; complex subunit ... See more keywords
Emodin in Rheum undulatum inhibits oxidative stress in the liver via AMPK with Hippo/Yap signalling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2020.1750658
Abstract: Abstract Context Emodin is a compound in Rheum undulatum Linne (Polygonaceae) that has been reported to exert anti-inflammatory, antibacterial, and antiallergic effects. Objective Oxidative stress is a causative agent of liver inflammation that may lead… read more here.
Keywords: inhibits oxidative; oxidative stress; via ampk; signalling pathway ... See more keywords
Sirt1 Inhibits Oxidative Stress in Vascular Endothelial Cells
Sign Up to like & getrecommendations! Published in 2017 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2017/7543973
Abstract: The vascular endothelium is a layer of cells lining the inner surface of vessels, serving as a barrier that mediates microenvironment homeostasis. Deterioration of either the structure or function of endothelial cells (ECs) results in… read more here.
Keywords: sirt1; inhibits oxidative; sirt1 inhibits; stress ... See more keywords