Eupatilin with PPARα agonistic effects inhibits TNFα-induced MMP signaling in HaCaT cells.
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DOI: 10.1016/j.bbrc.2017.09.043
Abstract: Eupatilin (5,7-dihydroxy-3,4,6-trimethoxyflavone) is a flavonoid compound exhibiting several beneficial biological activities, including neuroprotection, anti-cancer, antinociception, chondroprotection, anti-oxidation, and anti-inflammation. Our previous study demonstrated that eupatilin specifically activates peroxisome proliferator-activated receptor alpha (PPARα) through direct binding.… read more here.
Keywords: ppar; tnf induced; inhibits tnf; eupatilin ppar ... See more keywords