Impact of an emergency medicine pharmacist on initial antibiotic prophylaxis for open fractures in trauma patients
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DOI: 10.1016/j.ajem.2017.10.039
Abstract: Background Targeted antibiotic treatment reduces the infection risk of open fractures when soft tissue and bone are exposed to the environment. The risk of infection increases with higher degrees of injury. The Gustilo‐Anderson system was… read more here.
Keywords: medicine; impact emergency; emergency medicine; initial antibiotic ... See more keywords
Association of sputum microbiome with clinical outcome of initial antibiotic treatment in hospitalized patients with acute exacerbations of COPD.
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DOI: 10.1016/j.phrs.2020.105095
Abstract: Identification of risk factors for antibiotic treatment failure is urgently needed in acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Here we investigated the relationship between sputum microbiome and clinical outcome of choice of initial… read more here.
Keywords: treatment; sputum microbiome; antibiotic treatment; initial antibiotic ... See more keywords
Duration of initial antibiotic course is associated with recurrent relapse in protracted bacterial bronchitis
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DOI: 10.1136/archdischild-2019-317917
Abstract: Protracted bacterial bronchitis (PBB) is the leading cause of chronic wet cough in young children from developed countries. Despite its high prevalence there is a paucity of evidence to inform the optimal duration of treatment… read more here.
Keywords: duration; relapse; pbb; duration initial ... See more keywords
Does inappropriate initial antibiotic therapy affect in-hospital mortality of patients in the emergency department with Escherichia coli and Klebsiella pneumoniae bloodstream infections?
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DOI: 10.1177/2058738420942375
Abstract: Extended-spectrum β-lactamase (ESBL)-positive bloodstream infection (BSI) is on the rise worldwide. The purpose of this study is to evaluate the impact of inappropriate initial antibiotic therapy (IIAT) on in-hospital mortality of patients in the emergency… read more here.
Keywords: hospital mortality; inappropriate initial; time; mortality ... See more keywords
Bacterial Coinfection and Superinfection in Respiratory Syncytial Virus-Associated Acute Respiratory Illness: Prevalence, Pathogens, Initial Antibiotic-Prescribing Patterns and Outcomes
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DOI: 10.3390/tropicalmed8030148
Abstract: We aimed to determine the prevalence of bacterial coinfection (CoBact) and bacterial superinfection (SuperBact), the causative pathogens, the initial antibiotic-prescribing practice, and the associated clinical outcomes of hospitalized patients with respiratory syncytial virus-associated acute respiratory… read more here.
Keywords: initial antibiotic; antibiotic prescribing; bacterial coinfection; respiratory syncytial ... See more keywords