Efficacy and Safety of Initial Combination Therapy in Treatment-Naïve Type 2 Diabetes Patients: A Systematic Review and Meta-analysis
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DOI: 10.1007/s13300-018-0493-2
Abstract: IntroductionThe aim of this study was to evaluate the efficacy and safety of initial combination therapy compared with monotherapy in drug-naïve type 2 diabetes patients.MethodsMEDLINE, Embase and the Cochrane Central Register of Controlled Trials were… read more here.
Keywords: combination; combination therapies; initial combination; combination therapy ... See more keywords
Initial combination therapy for patients with pulmonary arterial hypertension (PAH): a budget impact analysis from the perspective of the Italian national healthcare system
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DOI: 10.1080/21678707.2018.1411259
Abstract: ABSTRACT Background: Initial combination therapy in patients with pulmonary arterial hypertension (PAH) WHO functional class (FC) II or III has demonstrated clinical benefits over initial monotherapy. The objective of this study is to compare the… read more here.
Keywords: impact; therapy patients; initial combination; therapy ... See more keywords
Cardiovascular and renal outcomes of initial combination therapy with glucose‐lowering agents versus a stepwise approach in newly diagnosed or treatment‐naïve type 2 diabetes: A systematic review and meta‐analysis
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DOI: 10.1111/dom.14715
Abstract: To evaluate the efficacy and safety of the initial combination therapy versus a stepwise approach in newly diagnosed type 2 diabetes (T2D) by conducting a systematic review and meta‐analysis of observational cohort studies and randomized… read more here.
Keywords: versus stepwise; initial combination; newly diagnosed; approach newly ... See more keywords
Haemodynamic effects of initial combination therapy in pulmonary arterial hypertension: a systematic review and meta-analysis
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DOI: 10.1183/23120541.00313-2022
Abstract: Background Although the initial use of combination treatment has been proven to be beneficial for patients’ clinical outcomes, there are scarce data on its haemodynamic effects. The objective of the present study was to evaluate… read more here.
Keywords: initial combination; haemodynamic effects; combination; therapy ... See more keywords
Positive Predictors for Response to Ambrisentan Combination Therapy in Pulmonary Arterial Hypertension.
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DOI: 10.1536/ihj.21-497
Abstract: The AMBITION study (NCT01178073) provided the first long-term clinical evidence for initial combination therapy with ambrisentan and tadalafil in patients with pulmonary arterial hypertension (PAH). Nevertheless, predictors of treatment response were not assessed.To identify predictors… read more here.
Keywords: predictors response; initial combination; therapy; combination therapy ... See more keywords