Using Generative Modeling to Endow with Potency Initially Inert Compounds with Good Bioavailability and Low Toxicity
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DOI: 10.1021/acs.jcim.3c01777
Abstract: In the early stages of drug development, large chemical libraries are typically screened to identify compounds of promising potency against the chosen targets. Often, however, the resulting hit compounds tend to have poor drug metabolism… read more here.
Keywords: inert compounds; using generative; initially inert; potency ... See more keywords