In vitro display evolution of IL-6R-binding unnatural peptides ribosomally initiated and cyclized with m-(chloromethyl)benzoic acid.
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DOI: 10.1016/j.bbrc.2020.11.123
Abstract: The interaction of the multifunctional cytokine interleukin (IL)-6 and its receptor (IL-6R) is involved in various diseases, including not only autoimmune diseases such as rheumatoid arthritis but also cancer and cytokine storms in coronavirus disease… read more here.
Keywords: initiated cyclized; binding unnatural; ribosomally initiated; cyclized chloromethyl ... See more keywords