Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis
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DOI: 10.1080/2162402x.2016.1267892
Abstract: ABSTRACT The cytokine-induced SH2-containing protein CIS belongs to the suppressor of cytokine signaling (SOCS) protein family. Here, we show the critical role of CIS in suppressing natural killer (NK) cell control of tumor initiation and… read more here.
Keywords: cis; cytokine signaling; metastasis; tumor initiation ... See more keywords