Quantitative Imaging of MicroRNA‐21 In Vivo for Real‐Time Monitoring of the Cancer Initiation and Progression
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202407348
Abstract: MicroRNA‐21 (MiR‐21) has been confirmed to be upregulated in tumors, and its abnormal expression is closely associated with tumor occurrence. However, the traditional imaging methods are limited to qualitative imaging of miR‐21, and no effective… read more here.
Keywords: cancer; initiation; initiation progression; cancer initiation ... See more keywords
Mitochondrial transcription factor A plays opposite roles in the initiation and progression of colitis‐associated cancer
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Communications"
DOI: 10.1002/cac2.12184
Abstract: Mitochondria are key regulators in cell proliferation and apoptosis. Alterations in mitochondrial function are closely associated with inflammation and tumorigenesis. This study aimed to investigate whether mitochondrial transcription factor A (TFAM), a key regulator of… read more here.
Keywords: transcription; initiation progression; mitochondrial transcription; transcription factor ... See more keywords
Fatty Acid Mediators in the Tumor Microenvironment.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-43093-1_8
Abstract: Patients with cancer frequently overexpress inflammatory cytokines with an associated neutrophilia both of which may be downregulated by diets with high omega-3 polyunsaturated fatty acids (ω-3 PUFA). The anti-inflammatory activity of dietary ω-3 PUFA has… read more here.
Keywords: fatty acid; tumor initiation; initiation progression; acid mediators ... See more keywords
Breaking through to the Other Side: Microenvironment Contributions to DCIS Initiation and Progression
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Mammary Gland Biology and Neoplasia"
DOI: 10.1007/s10911-018-9409-z
Abstract: Refinements in early detection, surgical and radiation therapy, and hormone receptor-targeted treatments have improved the survival rates for breast cancer patients. However, the ability to reliably identify which non-invasive lesions and localized tumors have the… read more here.
Keywords: side microenvironment; carcinoma; breaking side; initiation progression ... See more keywords
Oncogene-induced regulation of microRNA expression: Implications for cancer initiation, progression and therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.02.029
Abstract: A plethora of tumours have characteristic oncogenic mutations which are the main causes of malignant transformation, exerting their effects through multiple signalling pathways. Downstream of such pathways, microRNAs are small non-coding RNAs that negatively regulate… read more here.
Keywords: cancer; expression; initiation progression; oncogene induced ... See more keywords
A spatially explicit crop planting initiation and progression model for the conterminous United States
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Agronomy"
DOI: 10.1016/j.eja.2017.08.004
Abstract: Abstract The ability to accurately estimate crop planting date and planting progression has major implications in crop management, crop model applications, and in developing adaptation strategies for future climate change. The objectives of this study… read more here.
Keywords: initiation progression; model; planting initiation; progression ... See more keywords
Mundakkai-Chooralmala landslide: assessment of initiation, progression, and impact
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-07828-3
Abstract: Globally, the emergence of multi-hazard scenarios and cascaded disasters is significantly rising . During the 2024 monsoon in Wayanad District, Kerala, India, torrential rainfall triggered landslides, erosion, and flash floods, resulting in over 400 deaths.… read more here.
Keywords: landslide assessment; initiation progression; progression impact;
STEM-06. THE ROLE OF SHH SIGNALING PATHWAY IN RETINOBLASTOMA INITIATION AND PROGRESSION
Sign Up to like & getrecommendations! Published in 2024 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noae064.777
Abstract: Abstract BACKGROUND Retinoblastoma is a rare childhood cancer of the retina that shows the biallelic loss of RB1 in nearly 95% of cases. It was reported that SHH pathway proteins, such as SHH, GLI1, and… read more here.
Keywords: initiation; initiation progression; gli2; smo ... See more keywords
Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscape
Sign Up to like & getrecommendations! Published in 2017 at "Aging Cell"
DOI: 10.1111/acel.12621
Abstract: Ideally, disease modeling using patient‐derived induced pluripotent stem cells (iPSCs) enables analysis of disease initiation and progression. This requires any pathological features of the patient cells used for reprogramming to be eliminated during iPSC generation.… read more here.
Keywords: reprogramming progeria; initiation progression; epigenetic landscape; landscape ... See more keywords
Single-cell dissection of cellular and molecular features underlying human cervical squamous cell carcinoma initiation and progression
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.add8977
Abstract: Cervical squamous cell carcinoma (CESC) is a prototypical human cancer with well-characterized pathological stages of initiation and progression. However, high-resolution knowledge of the transcriptional programs underlying each stage of CESC is lacking, and important questions… read more here.
Keywords: cell; initiation progression; progression; squamous cell ... See more keywords
TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-1214
Abstract: Although numerous epigenetic aberrancies accumulate in melanoma, their contribution to initiation and progression remain unclear. The epigenetic mark 5-hydroxymethylcytosine (5hmC), generated through TET-mediated DNA modification, is now referred to as the sixth base of DNA… read more here.
Keywords: tet2; initiation; progression; initiation progression ... See more keywords