Genetic Lineage Tracing of Pericardial Cavity Macrophages in the Injured Heart
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DOI: 10.1161/circresaha.122.320567
Abstract: Background: Macrophages play an important role in cardiac repair after myocardial infarction (MI). In addition to the resident macrophages and blood-derived monocytes, Gata6+ cavity macrophages located in the pericardial space were recently reported to relocate… read more here.
Keywords: cavity macrophages; injured heart; lineage tracing; heart ... See more keywords
Fibroblast GSK-3α Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured Heart
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DOI: 10.1161/circresaha.122.321431
Abstract: Background: Heart failure is the leading cause of mortality, morbidity, and health care expenditures worldwide. Numerous studies have implicated GSK-3 (glycogen synthase kinase-3) as a promising therapeutic target for cardiovascular diseases. GSK-3 isoforms seem to… read more here.
Keywords: mek erk; injured heart; heart; gsk ... See more keywords
Advances in Nanomaterials for Injured Heart Repair
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DOI: 10.3389/fbioe.2021.686684
Abstract: Atherosclerotic cardiovascular disease (ASCVD) is one of the leading causes of mortality worldwide. Because of the limited regenerative capacity of adult myocardium to compensate for the loss of heart tissue after ischemic infarction, scientists have… read more here.
Keywords: injured heart; heart; advances nanomaterials; nanomaterials injured ... See more keywords
Cardiac regeneration: Options for repairing the injured heart
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DOI: 10.3389/fcvm.2022.981982
Abstract: Cardiac regeneration is one of the grand challenges in repairing injured human hearts. Numerous studies of signaling pathways and metabolism on cardiac development and disease pave the way for endogenous cardiomyocyte regeneration. New drug delivery… read more here.
Keywords: regeneration; cell; cardiac regeneration; repairing injured ... See more keywords