AC105 Increases Extracellular Magnesium Delivery and Reduces Excitotoxic Glutamate Exposure within Injured Spinal Cords in Rats
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurotrauma"
DOI: 10.1089/neu.2016.4607
Abstract: Abstract Magnesium (Mg2+) homeostasis is impaired following spinal cord injury (SCI) and the loss of extracellular Mg2+ contributes to secondary injury by various mechanisms, including glutamate neurotoxicity. The neuroprotective effects of high dose Mg2+ supplementation… read more here.
Keywords: injured spinal; delivery; magnesium; mg2 ... See more keywords
Repair mechanism of astrocytes and non-astrocytes in spinal cord injury.
Sign Up to like & getrecommendations! Published in 2020 at "World journal of clinical cases"
DOI: 10.12998/wjcc.v8.i5.854
Abstract: BACKGROUND Spinal cord injury (SCI) is a destructive disease that incurs huge personal and social costs, and there is no effective treatment. Although the pathogenesis and treatment mechanism of SCI has always been a strong… read more here.
Keywords: mechanism; cord; injured spinal; non injured ... See more keywords
Passive Clearing and 3D Lightsheet Imaging of the Intact and Injured Spinal Cord in Mice
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.684792
Abstract: The spinal cord contains a diverse array of sensory and motor circuits that are essential for normal function. Spinal cord injury (SCI) permanently disrupts neural circuits through initial mechanical damage, as well as a cascade… read more here.
Keywords: passive clearing; cord; injured spinal; tissue ... See more keywords
Neurogenesis potential of oligodendrocyte precursor cells from oligospheres and injured spinal cord
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1049562
Abstract: Severe traumatic spinal cord injury (SCI) leads to long-lasting oligodendrocyte death and extensive demyelination in the lesion area. Oligodendrocyte progenitor cells (OPCs) are the reservoir of new mature oligodendrocytes during damaged myelin regeneration, which also… read more here.
Keywords: injured spinal; oligospheres injured; oligodendrocyte; neurogenesis potential ... See more keywords
Repair of the Injured Spinal Cord by Schwann Cell Transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.800513
Abstract: Spinal cord injury (SCI) can result in sensorimotor impairments or disability. Studies of the cellular response to SCI have increased our understanding of nerve regenerative failure following spinal cord trauma. Biological, engineering and rehabilitation strategies… read more here.
Keywords: injured spinal; cell transplantation; sci; transplantation ... See more keywords