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Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0256035
Abstract: Background Chloroquine was promoted as a COVID-19 therapeutic early in the pandemic. Most countries have since discontinued the use of chloroquine due to lack of evidence of any benefit and the risk of severe adverse…
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Keywords:
heart;
injury heart;
heart failure;
heart injury ... See more keywords
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Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666170608111917
Abstract: BACKGROUND Ischemia-reperfusion (I/R) injury of the heart as a consequence of myocardial infarction or cardiac surgery represents a serious clinical problem. One of the most prominent mechanisms of I/R injury is the development of oxidative…
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Keywords:
heart;
injury heart;
beneficial effects;
ischemia reperfusion ... See more keywords
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Published in 2020 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v19i6.8
Abstract: Purpose: To investigate the effect of morphine preconditioning on myocardial ischemia reperfusion injury in heart failure rats, and the mechanism(s) of action involved Methods: Seventy-two healthy male Sprague-Dawley rats were assigned to 4 groups: sham,…
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Keywords:
morphine;
bcl;
bcl bax;
injury heart ... See more keywords