The innervation of the kidney in renal injury and inflammation: a cause and consequence of deranged cardiovascular control
Sign Up to like & getrecommendations! Published in 2017 at "Acta Physiologica"
DOI: 10.1111/apha.12856
Abstract: Extensive investigations have revealed that renal sympathetic nerves regulate renin secretion, tubular fluid reabsorption and renal haemodynamics which can impact on cardiovascular homoeostasis normally and in pathophysiological states. The significance of the renal afferent innervation… read more here.
Keywords: control; renal afferent; injury inflammation; innervation ... See more keywords
Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abk2709
Abstract: The role of N6-methyladenosine (m6A) modifications in renal diseases is largely unknown. Here, we characterized the role of N6-adenosine-methyltransferase-like 3 (METTL3), whose expression is elevated in renal tubules in different acute kidney injury (AKI) models… read more here.
Keywords: renal injury; m6a modifications; injury inflammation; mettl3 ... See more keywords
MiR-32-5p/AIDA Mediates OxLDL-Induced Endothelial Injury and Inflammation.
Sign Up to like & getrecommendations! Published in 2022 at "International heart journal"
DOI: 10.1536/ihj.22-067
Abstract: The role of endothelial injury and inflammation in atherosclerosis has been well established. miRNAs have been found to be key regulators in the development of atherosclerosis. Here we investigated whether miR-32-5p and its predicted target… read more here.
Keywords: endothelial injury; mir; injury inflammation; oxldl induced ... See more keywords
CD73 Attenuates Alcohol-Induced Liver Injury and Inflammation via Blocking TLR4/MyD88/NF-κB Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s341680
Abstract: Background Alcoholic liver disease (ALD) is liver damage caused by long-term drinking. Inflammation plays a central role in the progression of ALD. CD73 is a ubiquitously expressed glycosylphosphatidylinositol-anchored glycoprotein that is a key enzyme that… read more here.
Keywords: inflammation; cd73; liver injury; injury inflammation ... See more keywords
Mitofilin Heterozygote Mice Display an Increase in Myocardial Injury and Inflammation after Ischemia/Reperfusion
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DOI: 10.3390/antiox12040921
Abstract: Mitochondrial inner membrane protein (Mitofilin/Mic60) is part of a big complex that constituent the mitochondrial inner membrane organizing system (MINOS), which plays a critical role in maintaining mitochondrial architecture and function. We recently showed that… read more here.
Keywords: myocardial injury; increase; injury inflammation; mice ... See more keywords
A Newly Isolated Alcaligenes faecalis ANSA176 with the Capability of Alleviating Immune Injury and Inflammation through Efficiently Degrading Ochratoxin A
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DOI: 10.3390/toxins14080569
Abstract: Ochratoxin A (OTA) is one of the most prevalent mycotoxins that threatens food and feed safety. Biodegradation of OTA has gained much attention. In this study, an Alcaligenes faecalis strain named ANSA176, with a strong… read more here.
Keywords: ota; faecalis ansa176; injury inflammation; immune injury ... See more keywords
Modafinil ameliorated pancreatic injury and inflammation through upregulating SNIP1.
Sign Up to like & getrecommendations! Published in 2020 at "General physiology and biophysics"
DOI: 10.4149/gpb_2020016
Abstract: Acute pancreatitis (AP) is the inflammatory response of the exocrine pancreas to various causes. Modafinil has significant anti-inflammation and anti-oxidation effects. No experiment has assessed the effects of modafinil on AP. Thus, the study aims… read more here.
Keywords: modafinil ameliorated; pancreatic injury; inflammation; injury inflammation ... See more keywords