Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Neurochemical Research"
DOI: 10.1007/s11064-017-2293-x
Abstract: Increasing evidence demonstrates inflammation contributes to neuronal death following cerebral ischemia. Lycium barbarum polysaccharide (LBP) has been reported to prevent scopolamine-induced cognitive and memory deficits. We recently indicated that LBP exerts neuroprotective effect against focal… read more here.
Keywords: cerebral ischemic; ischemic injury; focal cerebral; injury mice ... See more keywords
A Selective TRPC3 Inhibitor Pyr3 Attenuates Myocardial Ischemia/Reperfusion Injury in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Current Medical Science"
DOI: 10.1007/s11596-020-2293-y
Abstract: An emerging body of evidence indicates that transient receptor potential TRP channels act as important mediators for a wide variety of physiological functions and are potential targets for drug discovery. Our previous study has identified… read more here.
Keywords: trpc3 inhibitor; pyr3; injury mice; inhibitor pyr3 ... See more keywords
MicroRNA-24-3p alleviates hepatic ischemia and reperfusion injury in mice through the repression of STING signaling.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.10.182
Abstract: Ischemia and reperfusion (I/R) injury is a common cause of hepatocyte injury and liver dysfunction during liver transplantation, but its mechanism is needed further explored. We aimed to investigate whether STING pathway activation is involved… read more here.
Keywords: injury mice; mice; ischemia reperfusion; reperfusion injury ... See more keywords
Niclosamide ethanolamine improves kidney injury in db/db mice.
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2018.08.003
Abstract: AIMS Early diabetic kidney disease (DKD) is characterized by renal hypertrophy and albuminuria. The mTOR signal pathway is closely related to DKD. This study was performed to determine the renal protection of niclosamide ethanolamine salt… read more here.
Keywords: kidney injury; injury mice; niclosamide ethanolamine; kidney ... See more keywords
Alpinetin protects against hepatic ischemia/reperfusion injury in mice by inhibiting the NF-κB/MAPK signaling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107527
Abstract: Liver damage induced by ischemia/reperfusion (I/R) remains a primary issue in liver transplantation and resection. Alpinetin, a novel plant flavonoid derived from Alpinia katsumadai Hayata, is widely used to treat various inflammatory diseases. However, the… read more here.
Keywords: signaling pathways; reperfusion; injury mice; injury ... See more keywords
Amelioration of alcohol-induced liver injury in mice by ginsenosides in ginseng wine
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2019.01.014
Abstract: Abstract We optimized conditions for preparation of ginseng wine and explored hepatoprotective effects of ginsenosides against alcohol-induced liver injury in mice by transcriptomics analyses. Mice were treated by daily intragastric administration of water, 55%-ethanol, or… read more here.
Keywords: induced liver; alcohol; injury mice; liver injury ... See more keywords
Crepidiastrum denticulatum Extract Ameliorates Kidney Ischemia-Reperfusion Injury in Mice.
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2018.02.048
Abstract: BACKGROUND Crepidiastrum denticulatum (CD) is a well-known, traditionally consumed vegetable in Korea, which was recently reported to contain bioactive compounds with detoxification and antioxidant properties. Ischemia-reperfusion injury (IRI) is a major problem after renal transplantation.… read more here.
Keywords: crepidiastrum denticulatum; reperfusion; injury mice; ischemia reperfusion ... See more keywords
Propionate Ameliorates Alcohol-Induced Liver Injury in Mice via the Gut-Liver Axis: Focus on the Improvement of Intestinal Permeability.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c00633
Abstract: Alcohol-related liver disease (ALD) is a major cause of chronic liver disease worldwide with limited therapeutic options. Here, we first revealed the promising beneficial effect of gut microbiota-derived propionate on alcoholic liver injury in mice.… read more here.
Keywords: gut; injury mice; liver injury; mice ... See more keywords
Protective effect of Qingluotongbi formula against Tripterygium wilfordii induced liver injury in mice by improving fatty acid β-oxidation and mitochondrial biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2157842
Abstract: Abstract Context Qingluotongbi formula (QLT) is a Chinese medicine compound consisting of Tripterygium wilfordii Hook. f. (Celastraceae, TW), Panax notoginseng (Burkill) F.H.Chen (Araliaceae, PN), Rehmannia glutinosa (Gaertn.) DC. (Orobanchaceae, RG), Sinomenium acutum (Thunb.) Rehder &… read more here.
Keywords: injury mice; liver injury; group; induced liver ... See more keywords
Hepatoprotective effect of total flavonoids from Glycyrrhiza uralensis Fisch in liver injury mice.
Sign Up to like & getrecommendations! Published in 2020 at "Natural product research"
DOI: 10.1080/14786419.2020.1824223
Abstract: This work aimed to investigate the hepatoprotective effect of total flavonoids from Glycyrrhiza uralensis. The main compounds in licorice total flavonoids (LTF) were isolated from Glycyrrhiza uralensis and their total content in LTF were more… read more here.
Keywords: hepatoprotective effect; effect total; injury mice; glycyrrhiza uralensis ... See more keywords
The effects of atorvastatin on the kidney injury in mice with pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.13128
Abstract: The present study investigated the effects of atorvastatin on kidney injury in mice with pulmonary fibrosis (PF). read more here.
Keywords: kidney injury; effects atorvastatin; mice pulmonary; injury mice ... See more keywords