Spherical α-helical polypeptide-mediated E2F1 silencing against myocardial ischemia-reperfusion injury (MIRI).
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DOI: 10.1039/d2bm01075e
Abstract: Apoptosis of cardiomyocytes is a critical outcome of myocardial ischemia-reperfusion injury (MIRI), which leads to the permanent impairment of cardiac function. Upregulated E2F1 is implicated in inducing cardiomyocyte apoptosis, and thus intervention of the E2F1… read more here.
Keywords: reperfusion injury; miri; myocardial ischemia; injury miri ... See more keywords