Decreased SIRT1 Activity Is Involved in the Acute Injury Response of Chondrocytes to Ex Vivo Injurious Mechanical Overload
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DOI: 10.3390/ijms24076521
Abstract: A better understanding of molecular events following cartilage injury is required to develop treatments that prevent or delay the onset of trauma-induced osteoarthritis. In this study, alterations to SIRT1 activity in bovine articular cartilage explants… read more here.
Keywords: sirt1 activity; mechanical overload; injury response; activity ... See more keywords