Amelioration of myocardial ischemia-reperfusion injury by SIRT4 involves mitochondrial protection and reduced apoptosis.
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DOI: 10.1016/j.bbrc.2018.05.113
Abstract: Apoptosis and mitochondria dysfunction are key contributors to myocardial ischemia-reperfusion (MI-R) injury. SIRT4, a mitochondrial-localized sirtuin, controls cellular energy metabolism and stress response, and is abundantly present in the heart, however, its role in MI-R… read more here.
Keywords: sirt4; injury sirt4; myocardial ischemia; ischemia reperfusion ... See more keywords