Rivastigmine ameliorates indomethacin experimentally induced gastric mucosal injury via activating α7nAChR with inhibiting oxidative stress and apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23147
Abstract: The current study aimed to investigate the potential ameliorative role of Rivastigmine (RIVA), the anti‐Alzheimer drug, against the gastric mucosal injury caused by indomethacin (IND). The rats were divided into four groups: group I was… read more here.
Keywords: injury via; gastric mucosal; via activating; induced gastric ... See more keywords
Luteoloside protects the vascular endothelium against iron overload injury via the ROS/ADMA/DDAH II/eNOS/NO pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(21)60110-3
Abstract: Iron overload injury is considered to be a part of blood stasis syndrome of arthralgia in traditional Chinese medicine. Its primary therapies include clearing heat and detoxification, activating blood circulation, and removing blood stasis. Lonicera… read more here.
Keywords: injury via; overload injury; ros; iron overload ... See more keywords
MiR-455-5p attenuates cerebral ischemic reperfusion injury via targeting FLT3.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000898
Abstract: Cerebral ischemia-reperfusion (I/R) injury is a terrible disease which results in the dysfunction and structural damage of brain tissues. Growing evidence implies that miR-455-5p is implicated in the regulation of pathogenesis of several diseases. The… read more here.
Keywords: injury via; reperfusion injury; cerebral injury; mir 455 ... See more keywords
TLR4 Enhances Cerebral Ischemia/Reperfusion Injury via Regulating NLRP3 Inflammasome and Autophagy
Sign Up to like & getrecommendations! Published in 2023 at "Mediators of Inflammation"
DOI: 10.1155/2023/9335166
Abstract: Ischemic stroke is a kind of central nervous disease characterized by high morbidity, high mortality, and high disability. Inflammation and autophagy play important roles in cerebral ischemia/reperfusion (CI/R) injury. The present study characterizes the effects… read more here.
Keywords: reperfusion injury; injury via; cerebral ischemia; injury ... See more keywords
Tim-1 alleviates lupus nephritis-induced podocyte injury via regulating autophagy
Sign Up to like & getrecommendations! Published in 2021 at "Central-European Journal of Immunology"
DOI: 10.5114/ceji.2021.109827
Abstract: Introduction Lupus nephritis (LN) is a complication of systemic lupus erythematosus (SLE) which seriously threatens the health of people. Tim-1 is known to be associated with the pathogenesis of SLE. However, the role of Tim-1… read more here.
Keywords: lupus nephritis; tim; injury; induced podocyte ... See more keywords
Keap-NRF2 signaling contributes to the Notch1 protected heart against ischemic reperfusion injury via regulating mitochondrial ROS generation and bioenergetics
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.63297
Abstract: Myocardial ischemia/reperfusion (I/R) injury is recognized as the leading cause of death worldwide. However, the molecular mechanisms involved in this process are still not fully understood. We previously reported that the combined action of Notch1… read more here.
Keywords: reperfusion injury; injury via; mitochondrial ros; nrf2 signaling ... See more keywords