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1
Published in 2017 at "Science Signaling"
DOI: 10.1126/scisignal.aaf8223
Abstract: E6AP exhibits tumor suppressor activity that may help stratify NSCLC patients. INK4/ARF repression in lung cancer by loss of E6AP The abundance of the cell cycle decelerator p16INK4a, encoded at the INK4/ARF locus, is decreased…
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Keywords:
arf locus;
expression;
ink4 arf;
lung cancer ... See more keywords
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2
Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.948351
Abstract: 9p21 locus is one of the most reproducible regions in genome-wide association studies (GWAS). The region harbors CDKN2A/B genes that code for p16INK4a, p15INK4b, and p14ARF proteins, and it also harbors a long gene desert…
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Keywords:
locus;
arf locus;
ink4 arf;
transcriptional regulation ... See more keywords