Subcutaneous administration of α-GalCer activates iNKT10 cells to promote M2 macrophage polarization and ameliorates chronic inflammation of obese adipose tissue.
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DOI: 10.1016/j.intimp.2019.105948
Abstract: OBJECTIVE The role of iNKT cells was investigated in chronic adipose tissue inflammation in obese mice after administration of α-GalCer in different pathways. METHODS C57BL/6J mice were fed high-fat diet (HFD) for 12 weeks to establish… read more here.
Keywords: inkt10 cells; tissue; inflammation obese; adipose tissue ... See more keywords