Arsenic metabolites; selenium; and AS3MT, MTHFR, AQP4, AQP9, SELENOP, INMT, and MT2A polymorphisms in Croatian‐Slovenian population from PHIME‐CROME study
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DOI: 10.1016/j.envres.2018.11.045
Abstract: ABSTRACT The relationships between inorganic arsenic (iAs) metabolism, selenium (Se) status, and genetic polymorphisms of various genes, commonly studied in populations exposed to high levels of iAs from drinking water, were studied in a Croatian‐Slovenian… read more here.
Keywords: methylation; croatian slovenian; pregnant women; non pregnant ... See more keywords
Indolethylamine-N-Methyltransferase Inhibits Proliferation and Promotes Apoptosis of Human Prostate Cancer Cells: A Mechanistic Exploration
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DOI: 10.3389/fcell.2022.805402
Abstract: Indolethylamine-N-methyltransferase (INMT) is a methyltransferase downregulated in lung cancer, meningioma, and prostate cancer; however, its role and mechanism in prostate cancer remain unclear. By analyzing The Cancer Genome Atlas (TCGA)-PRAD, we found that the expression… read more here.
Keywords: cancer; expression; inmt; methyltransferase ... See more keywords
Poor prognosis, hypomethylation, and immune infiltrates are associated with downregulation of INMT in head and neck squamous cell carcinoma
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DOI: 10.3389/fgene.2022.917344
Abstract: Background: Indiolethylamine-N-methyltransferase (INMT) is a methyltransferase responsible for transferring methyl groups from methyl donor SAM to its substrate. S-adenosyl-l-methionine (SAM), obtained from the methionine cycle, is a naturally occurring sulfonium compound that is vital to… read more here.
Keywords: methylation; cell; prognosis; inmt ... See more keywords