The Endoplasmic Reticulum ATP13A1 is Essential for MAVS‐Mediated Antiviral Innate Immunity
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202203831
Abstract: RIG‐I‐MAVS signaling pathway is essential for efficient innate immune response against virus infection. Though many components have been identified in RIG‐I pathway and it can be partially reconstituted in vitro, detailed mechanisms involved in cells… read more here.
Keywords: endoplasmic reticulum; antiviral innate; mediated antiviral; mavs ... See more keywords
The role of innate lymphoid cells in health and disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26250
Abstract: Innate lymphoid cells (ILCs) are kind of innate immune cells which can be divided into three main subsets according to their cytokine release profile, transcription factors, and surface markers. ILCs affect the initial stages of… read more here.
Keywords: innate; role innate; disease; innate lymphoid ... See more keywords
ER stress protein PERK promotes inappropriate innate immune responses and pathogenesis during RSV infection
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3a0520-322rr
Abstract: The activation of dendritic cells (DC) during respiratory viral infections is central to directing the immune response and the pathologic outcome. In these studies, the effect of RSV infection on development of ER stress responses… read more here.
Keywords: perk; innate; rsv infection; infection ... See more keywords
Interactions between the microbiota and innate and innate‐like lymphocytes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ri0917-378r
Abstract: The microbiota, which consists of commensal bacteria, fungi, and viruses, limits the colonization of pathogens at barrier tissues and promotes immune homeostasis. The latter is accomplished through the induction and regulation of both innate and… read more here.
Keywords: innate; like lymphocytes; innate innate; type innate ... See more keywords
TRIM21 promotes ubiquitination of SARS‐CoV‐2 nucleocapsid protein to regulate innate immunity
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28719
Abstract: The innate immune response is the first line of host defense against viral infections, but its role in immunity against SARS‐CoV‐2 remains unclear. By using immunoprecipitation coupled with mass spectroscopy, we observed that the E3… read more here.
Keywords: nucleocapsid protein; trim21; cov nucleocapsid; innate ... See more keywords
Role of Innate Genes in HIV Replication.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2017_29
Abstract: Cells use an elaborate innate immune surveillance and defense system against virus infections. Here, we discuss recent studies that reveal how HIV-1 is sensed by the innate immune system. Furthermore, we present mechanisms on the… read more here.
Keywords: innate; innate genes; genes hiv; innate response ... See more keywords
Evaluation of Innate Lymphoid Cells and Dendritic Cells Following Viral Vector Vaccination.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2168-4_8
Abstract: Recently, we have shown that fate of a vaccine is determined by the cytokine milieu in the innate immune compartment at the early stage of vaccination. Specifically, 24 h post-delivery, level of innate lymphoid cell type… read more here.
Keywords: innate; viral vector; vaccination; innate lymphoid ... See more keywords
RNA PAMPs as Molecular Tools for Evaluating RIG-I Function in Innate Immunity.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7237-1_6
Abstract: Pathogen recognition receptors (PRR)s and their cognate pathogen-associated molecular pattern (PAMP) represent the basis of innate immune activation and immune response induction driven by the host-pathogen interaction that occurs during microbial infection in humans and… read more here.
Keywords: innate; molecular tools; rig; pamps molecular ... See more keywords
Determination of the Fate and Function of Innate Lymphoid Cells Following Adoptive Transfer of Innate Lymphoid Cell Precursors.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7896-0_10
Abstract: Innate lymphoid cells are a heterogeneous family of tissue-resident and circulating lymphocytes that play an important role in host immunity. Recent studies have profiled the developmental pathways of mature ILCs and have identified ILC progenitors… read more here.
Keywords: innate; innate lymphoid; lymphoid cells; adoptive transfer ... See more keywords
Quantifying Human Innate Cytokine and Chemokine Responses Ex Vivo via Pattern Recognition Receptor Stimulation.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9591-2_6
Abstract: Linkages between human innate immune capacity, the environment in which we live, and the development of clinical tolerance versus a spectrum of disease phenotypes are a major focus of inflammatory disease research. While extensive epidemiologic… read more here.
Keywords: innate; human innate; receptor stimulation; innate immune ... See more keywords
Structural basis of NLR activation and innate immune signalling in plants
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DOI: 10.1007/s00251-021-01242-5
Abstract: Animals and plants have NLRs (nucleotide-binding leucine-rich repeat receptors) that recognize the presence of pathogens and initiate innate immune responses. In plants, there are three types of NLRs distinguished by their N-terminal domain: the CC… read more here.
Keywords: innate; innate immune; domain nlrs; immune signalling ... See more keywords