Articles with "innate antiviral" as a keyword



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Antiviral immunity: a link to bile acids

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Published in 2019 at "Cell Research"

DOI: 10.1038/s41422-019-0148-5

Abstract: A recent study in Cell Research by Hu et al. describes a novel function of intracellular bile acids (BAs), a class of cholesterolderived metabolites, which activate several key innate antiviral signaling components through the TGR5-β-arrestinSRC… read more here.

Keywords: innate antiviral; immune; response; infection ... See more keywords
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Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2122805119

Abstract: Significance Virus-induced signal adaptor (VISA)/mitochondrial antiviral signaling protein (MAVS) is an essential adaptor protein in innate immune response to RNA viruses; understanding how VISA is regulated is important for the treatment of infectious diseases. In… read more here.

Keywords: tankyrases inhibit; response; rnf146; antiviral response ... See more keywords
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Estradiol‐regulated innate antiviral responses of human endometrial stromal fibroblasts

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Published in 2018 at "American Journal of Reproductive Immunology"

DOI: 10.1111/aji.13042

Abstract: The contribution of fibroblasts to innate immune protection of the human female reproductive tract (FRT) against viral pathogens is relatively unknown. read more here.

Keywords: innate antiviral; human endometrial; regulated innate; responses human ... See more keywords
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Cytoplasmic RNA sensors and their interplay with RNA-binding partners in innate antiviral response: theme and variations

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Published in 2022 at "RNA"

DOI: 10.1261/rna.079016.121

Abstract: Sensing of pathogen-associated molecular patterns including viral RNA by innate immunity represents the first line of defense against viral infection. In addition to RIG-I-like receptors and NOD-like receptors, several other RNA sensors are known to… read more here.

Keywords: rna binding; rna; rna sensors; innate antiviral ... See more keywords
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LPA maintains innate antiviral immunity in a pro-active state via STK38L-mediated IRF3 Ser303 phosphorylation.

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Published in 2022 at "Cell reports"

DOI: 10.2139/ssrn.4124631

Abstract: Innate immunity is critical for the early detection and elimination of viral invasion. Extracellular signals are crucial for host resistance; however, how extracellular factors prepare the innate immunity for rapid antiviral response remains elusive. Here,… read more here.

Keywords: state; immunity; pro active; innate antiviral ... See more keywords
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Modulation of Innate Antiviral Immune Response by Porcine Enteric Coronavirus

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Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.845137

Abstract: Host’s innate immunity is the front-line defense against viral infections, but some viruses have evolved multiple strategies for evasion of antiviral innate immunity. The porcine enteric coronaviruses (PECs) consist of porcine epidemic diarrhea virus (PEDV),… read more here.

Keywords: porcine enteric; enteric coronaviruses; coronavirus; antiviral immune ... See more keywords