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Published in 2019 at "Mitochondrion"
DOI: 10.1016/j.mito.2019.06.001
Abstract: Proteins embedded in the inner mitochondrial membrane (IMM) perform essential cellular functions. Maintaining the folding state of these proteins is therefore of the utmost importance, and this is ensured by IMM chaperones and proteases that…
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Keywords:
protein;
protein misfolding;
imm;
inner mitochondrial ... See more keywords
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Published in 2020 at "Mitochondrion"
DOI: 10.1016/j.mito.2020.11.001
Abstract: The efficient production of energy via oxidative phosphorylation is essential to the growth, survival, and reproduction of eukaryotes. The behavior (position of, and communication between, mitochondria) and morphology of mitochondria play key roles in efficient…
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Keywords:
inter mitochondrial;
density;
proportion inter;
inner mitochondrial ... See more keywords
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Published in 2021 at "Redox Biology"
DOI: 10.1016/j.redox.2021.102055
Abstract: Background Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) are linked to several mitochondrial alterations. Cigarette smoke (CS) alters the structure and function of mitochondria. OPA1 is the…
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Keywords:
opa1 isoforms;
opa1;
copd;
inner mitochondrial ... See more keywords
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Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1916414117
Abstract: Significance The mitochondria, organelles that produce the largest amounts of ATP and reactive oxygen species (mROS) in living cells, are equipped with a universal mechanism that can completely prevent mROS production. This mechanism consists of…
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Keywords:
depolarization inner;
mild depolarization;
mitochondrial membrane;
inner mitochondrial ... See more keywords
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Published in 2021 at "Life Science Alliance"
DOI: 10.26508/lsa.202000806
Abstract: The multifunctional Ser/Thr kinase AURKA uses the Inner Mitochondrial Membrane receptor PHB2 and MAP1LC3 as a signalling platform to orchestrate the elimination of dysfunctional mitochondria. Epithelial and haematologic tumours often show the overexpression of the…
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Keywords:
kinase;
phb2;
inner mitochondrial;
tripartite complex ... See more keywords
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Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.542950
Abstract: Mitochondrial enzymes involved in energy transformation are organized into multiprotein complexes that channel the reaction intermediates for efficient ATP production. Three of the mammalian urea cycle enzymes: N-acetylglutamate synthase (NAGS), carbamylphosphate synthetase 1 (CPS1), and…
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Keywords:
cycle;
mitochondrial enzymes;
urea cycle;
inner mitochondrial ... See more keywords