Norepinephrine activates β1‐adrenergic receptors at the inner nuclear membrane in astrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24219
Abstract: Norepinephrine exerts powerful influences on the metabolic, neuroprotective and immunoregulatory functions of astrocytes. Until recently, all effects of norepinephrine were believed to be mediated by receptors localized exclusively to the plasma membrane. However, recent studies… read more here.
Keywords: inner nuclear; receptors localized; nuclear membrane; adrenergic receptors ... See more keywords
Fluorescent Labeling of the Nuclear Envelope Without Relying on Inner Nuclear Membrane Proteins.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1258-3_1
Abstract: The nuclear envelope (NE), a double membrane that separates nuclear components from the cytoplasm, undergoes a breakdown and reformation during cell division. To trace NE dynamics, the NE needs to be labeled with a fluorescent… read more here.
Keywords: nuclear envelope; nuclear membrane; inner nuclear; fluorescent labeling ... See more keywords
ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-05889-9
Abstract: Vesicle-mediated nucleocytoplasmic transport is a nuclear pore-independent mechanism for the nuclear export of macromolecular complexes, but the molecular basis for this transport remains largely unknown. Here we show that endosomal sorting complex required for transport-III… read more here.
Keywords: escrt iii; iii; nuclear membrane; transport ... See more keywords
Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-26574-4
Abstract: Precise control of gene expression during differentiation relies on the interplay of chromatin and nuclear structure. Despite an established contribution of nuclear membrane proteins to developmental gene regulation, little is known regarding the role of… read more here.
Keywords: protein; cell differentiation; differentiation; inner nuclear ... See more keywords
Towards Understanding Inner Nuclear Membrane Protein Degradation in Plants.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of experimental botany"
DOI: 10.1093/jxb/erac037
Abstract: The inner nuclear membrane (INM) hosts a unique set of membrane proteins that play essential roles in various aspects of the nuclear function. However, overaccumulation or malfunction of INM protein has been associated with a… read more here.
Keywords: nuclear membrane; membrane; degradation; protein degradation ... See more keywords
Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1186
Abstract: Abstract The dynamic association of chromosomes with the nuclear envelope (NE) is essential for chromosome maintenance. Schizosaccharomyces pombe inner nuclear membrane protein Bqt4 plays a critical role in connecting telomeres to the NE, mainly through… read more here.
Keywords: protein; nuclear envelope; nuclear membrane; bqt4 ... See more keywords
Monitoring of chromatin organization in live cells by FRIC. Effects of the inner nuclear membrane protein Samp1
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz123
Abstract: Abstract In most cells, transcriptionally inactive heterochromatin is preferentially localized in the nuclear periphery and transcriptionally active euchromatin is localized in the nuclear interior. Different cell types display characteristic chromatin distribution patterns, which change dramatically… read more here.
Keywords: heterochromatin; live cells; nuclear membrane; inner nuclear ... See more keywords
Regulated degradation of the inner nuclear membrane protein SUN2 maintains nuclear envelope architecture and function
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.07.15.500172
Abstract: Nuclear architecture and functions depend on dynamic interactions between nuclear components (such as chromatin) and inner nuclear membrane (INM) proteins. Mutations in INM proteins interfering with these interactions result in disease. However, mechanisms controlling the… read more here.
Keywords: inner nuclear; sun2; architecture; membrane ... See more keywords
The inner nuclear membrane protein NEMP1 supports nuclear envelope openings and enucleation of erythroblasts
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Biology"
DOI: 10.1371/journal.pbio.3001811
Abstract: Nuclear envelope membrane proteins (NEMPs) are a conserved family of nuclear envelope (NE) proteins that reside within the inner nuclear membrane (INM). Even though Nemp1 knockout (KO) mice are overtly normal, they display a pronounced… read more here.
Keywords: inner nuclear; enucleation; nuclear envelope; erythropoiesis ... See more keywords
The Role of the Inner Nuclear Layer for Perception of Persisting Tiling Inside a Monocular Scotoma
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12111542
Abstract: We report two patients, one with and one without long-term persistent tiling inside an arcuate macular scotoma. In both cases, the scotoma was caused by a cilioretinal artery occlusion. Both patients were almost identical regarding… read more here.
Keywords: tiling inside; nuclear layer; inner nuclear; persistent tiling ... See more keywords