Innovation of 6-sulfonamide-2H-chromene derivatives as antidiabetic agents targeting α-amylase, α-glycosidase, and PPAR-γ inhibitors with in silico molecular docking simulation
Sign Up to like & getrecommendations! Published in 2024 at "RSC Advances"
DOI: 10.1039/d4ra02143f
Abstract: A new series of 2-imino or 2-oxo-2H-chromene-6-sulfonamide derivatives 2–9 with potential anti-diabetic activity were designed and synthesized. The new 6-sulfonamide chromenes were synthesized by reacting 3-formyl-4-hydroxybenzenesulfonyl chloride with activated methylene derivatives in the presence of… read more here.
Keywords: ppar; sulfonamide chromene; ic50 values; innovation sulfonamide ... See more keywords