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Published in 2022 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s0266462322000095
Abstract: Abstract Objectives An increasing number of innovative therapies (e.g., gene- and cell-based treatments) have been developed in the past 20 years. Despite the significant clinical potential of these therapies, access delays may arise because of…
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Keywords:
value based;
innovative therapies;
negotiation framework;
value ... See more keywords
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Published in 2018 at "Nature"
DOI: 10.1038/d41586-018-06713-6
Abstract: From lasers to electrical fields, clinicians are venturing off the beaten path to outflank a formidable foe.From lasers to electrical fields, clinicians are venturing off the beaten path to outflank a formidable foe.
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Keywords:
therapies could;
could break;
brain cancer;
cancer stalemate ... See more keywords
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Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.11524
Abstract: 11524Background: Chemotherapy and surgery achieve a 5-year event-free survival of 60-70% in localized osteosarcoma (OS), but little additional progress has been made in recent decades. Clinical res...
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Keywords:
drug repurposing;
source innovative;
oncology;
therapies osteosarcoma ... See more keywords
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Published in 2018 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2018.00464
Abstract: Targeting the Immune Checkpoint molecules (ICs; CTLA-4, PD-1, PD-L1/2, and others) which provide inhibitory signals to T cells, dramatically improves survival in hard-to-treat tumors. The establishment of an immunosuppressive environment prevents endogenous immune response in…
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Keywords:
checkpoints innovative;
therapies glioblastoma;
innovative therapies;
immune checkpoints ... See more keywords