Activity of Cabazitaxel in Metastatic or Inoperable Locally Advanced Dedifferentiated Liposarcoma: A Phase 2 Study of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG).
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DOI: 10.1001/jamaoncol.2022.3218
Abstract: Importance Treatment options for patients with unresectable and/or metastatic dedifferentiated liposarcoma (DDLPS) are limited. New drugs are required. Objective To assess whether cabazitaxel demonstrated sufficient antitumor activity in patients with metastatic or inoperable locally advanced… read more here.
Keywords: locally advanced; metastatic inoperable; dedifferentiated liposarcoma; activity ... See more keywords
Geriatric assessment may help decision-making in elderly patients with inoperable, locally advanced non-small-cell lung cancer
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DOI: 10.1038/bjc.2017.455
Abstract: Background:Although concurrent chemoradiotherapy (cCRT) increases survival in patients with inoperable, locally advanced non-small-cell lung cancer (NSCLC), there is no consensus on the treatment of elderly patients. The aim of this study was to determine the… read more here.
Keywords: patients inoperable; inoperable locally; elderly patients; geriatric assessment ... See more keywords
Abstract OT1-01-01: IMpassion131: A phase III study comparing 1L atezolizumab with paclitaxel vs placebo with paclitaxel in treatment-naive patients with inoperable locally advanced or metastatic triple negative breast cancer (TNBC)
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DOI: 10.1158/1538-7445.sabcs17-ot1-01-01
Abstract: Background: Chemotherapy (including paclitaxel) remains the predominant treatment for metastatic TNBC but clinical outcomes remain poor. Therefore, new therapeutic approaches are needed. Atezolizumab blocks the binding of PD-L1 to its receptors PD-1 and B7.1, thus… read more here.
Keywords: advanced metastatic; inoperable locally; tnbc; cancer ... See more keywords
Moderately hypo-fractionated radiotherapy combined with S-1 in inoperable locally advanced esophageal squamous cell carcinoma: A prospective, single-arm phase II study (GASTO-1045)
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DOI: 10.3389/fonc.2023.1138304
Abstract: Purpose We launched this prospective phase II single-arm trial on the combination of moderately hypo-fractionated radiotherapy and S-1, to explore the safety and efficacy of the new potent regimen in inoperable locally advanced esophageal squamous… read more here.
Keywords: moderately hypo; fractionated radiotherapy; hypo fractionated; radiotherapy ... See more keywords
Radical radiotherapy or chemoradiotherapy for inoperable, locally advanced, non-small cell lung cancer: Analysis of patient profile, treatment approaches, and outcomes for 213 patients at a tertiary cancer center.
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DOI: 10.4103/ijc.ijc_469_17
Abstract: INTRODUCTION Radical radiotherapy (RT) with curative intent, with or without chemotherapy, is the standard treatment for inoperable, locally advanced nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS We retrospectively reviewed the data for all 288… read more here.
Keywords: treatment; inoperable locally; radiotherapy; chemoradiotherapy ... See more keywords