2‐O‐Acetyl‐3,4,5,6‐tetra‐O‐benzyl‐d‐myo‐inosityl diphenylphosphate: A new useful intermediate to inositol phosphate and phospholipids
Sign Up to like & getrecommendations! Published in 2022 at "Chirality"
DOI: 10.1002/chir.23457
Abstract: Abstract Inositol phosphates and inositol phospholipids are ubiquitous in biochemistry and play a central role in cell signaling and regulation events. For this reason, their synthesis has attracted widespread interest. This paper describes the preparation… read more here.
Keywords: inositol; acetyl tetra; inositol phosphate; tetra benzyl ... See more keywords
Modification and application of an in vitro assay to examine inositol phosphate degradation in the digestive tract of poultry.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.8297
Abstract: BACKGROUND An in vitro assay was modified to study the disappearance of inositol hexakisphosphate (InsP6 ) and the formation of lower inositol phosphate (InsP) isomers in the poultry digestive tract, and three experiments investigated the… read more here.
Keywords: inositol; vitro assay; inositol phosphate; digestive tract ... See more keywords
Structural analyses of inositol phosphate second messengers bound to signaling effector proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2019.100667
Abstract: The higher-order inositol phosphate second messengers inositol tetrakisphosphate (IP4), inositol pentakisphosphate (IP5) and inositol hexakisphosphate (IP6) are important signaling molecules that regulate DNA-damage repair, cohesin dynamics, RNA-editing, retroviral assembly, nuclear transport, phosphorylation, acetylation, crotonylation, and… read more here.
Keywords: inositol; inositol phosphate; second messengers; effector proteins ... See more keywords
Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00981
Abstract: The myo-inositol-1-phosphate synthase (MIPS) ortholog Ari2, which is encoded in the aristeromycin biosynthetic gene clus-ter, catalyzes the formation of five-membered cyclitol phos-phate using D-fructose 6-phosphate (F6P) as a substrate. To understand the stereochemistry during the… read more here.
Keywords: myo inositol; stereochemistry; ari2; inositol phosphate ... See more keywords
In-silico studies on Myo inositol-1-phosphate synthase of Leishmania donovani in search of anti-leishmaniasis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1847194
Abstract: Abstract Myo-inositol is one of the vital nutritional requirements for the Leishmania parasites’ survival and virulence in the mammalian host. . Myo-inositol-1-phosphate synthase (MIPS) is responsible for the synthesis of myo-inositol in Leishmania, which plays… read more here.
Keywords: inositol phosphate; phosphate synthase; myo inositol; synthase ... See more keywords
Use of Protein Kinase–Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "SLAS Discovery"
DOI: 10.1177/2472555218775323
Abstract: Inositol hexakisphosphate kinases (IP6Ks) regulate a myriad of cellular processes, not only through their catalytic activity (which synthesizes InsP7, a multifunctional inositol pyrophosphate signaling molecule) but also through protein–protein interactions. To further study the enzymatic… read more here.
Keywords: kinase; inositol phosphate; kinase focused; focused compound ... See more keywords
Phytase dose-dependent response of kidney inositol phosphate levels in poultry
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DOI: 10.1371/journal.pone.0275742
Abstract: Phytases, enzymes that degrade phytate present in feedstuffs, are widely added to the diets of monogastric animals. Many studies have correlated phytase addition with improved animal productivity and a subset of these have sought to… read more here.
Keywords: inositol; inositol phosphates; ins ins; kidney ... See more keywords
Impacts of dietary calcium, phytate, and phytase on inositol hexakisphosphate degradation and inositol phosphate release in different segments of digestive tract of broilers
Sign Up to like & getrecommendations! Published in 2017 at "Poultry Science"
DOI: 10.3382/ps/pex170
Abstract: &NA; A total of 720 straight‐run Heritage 56 M × fast feathering Cobb 500F broiler chickens was fed from 11 to 13 d of age to determine the impacts of dietary calcium (Ca), phytate phosphorus… read more here.
Keywords: dietary calcium; inositol; phytase; inositol phosphate ... See more keywords
Adsorption of Inositol Phosphate on Hydroxyapatite Powder with High Specific Surface Area
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DOI: 10.3390/ma15062176
Abstract: Chelate-setting calcium-phosphate cements (CPCs) have been developed using inositol phosphate (IP6) as a chelating agent. However, the compressive strength of the CPC fabricated from a commercially available hydroxyapatite (HAp) powder was approximately 10 MPa. In… read more here.
Keywords: phosphate; adsorption; inositol phosphate; specific surface ... See more keywords