Articles with "inositol requiring" as a keyword



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MicroRNAs: Unfolding the Link Between Inositol‐Requiring Enzyme 1α and Fatty Liver

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Published in 2019 at "Hepatology"

DOI: 10.1002/hep.30427

Abstract: Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of abnormal liver chemistry tests in the United States and western world. The mechanisms underlying hepatic steatosis and the progression to nonalcoholic steatohepatitis (NASH)… read more here.

Keywords: inositol requiring; micrornas unfolding; fatty liver; liver ... See more keywords
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Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain

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Published in 2018 at "ACS Omega"

DOI: 10.1021/acsomega.8b01404

Abstract: Inositol-requiring enzyme 1 (IRE1) is an orchestrator of the unfolded protein response (UPR), the cellular response to endoplasmic reticulum (ER) stress that plays a crucial role in tumor development. IRE1 signaling is the most evolutionary… read more here.

Keywords: inositol requiring; kinase; kinase domain; ire1 kinase ... See more keywords