Distinct cerebral cortical perfusion patterns in idiopathic normal‐pressure hydrocephalus
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.25974
Abstract: The aims of the study are to evaluate idiopathic normal‐pressure hydrocephalus (INPH)‐related cerebral blood flow (CBF) abnormalities and to investigate their relation to cortical thickness in INPH patients. We investigated cortical CBF utilizing surface‐based early‐phase… read more here.
Keywords: normal pressure; healthy controls; inph patients; perfusion ... See more keywords
Reduced Striatal DAT Uptake Normalizes After Shunt in Normal‐Pressure Hydrocephalus
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders"
DOI: 10.1002/mds.28336
Abstract: Idiopathic normal pressure hydrocephalus (iNPH) is characterized by gait disturbance, cognitive impairment, parkinsonian signs, and urinary incontinence, responsive to shunt surgery. There is evidence that dopamine transporter imaging (DAT-SPECT) is reduced in 30%–60% of iNPH… read more here.
Keywords: normal pressure; pressure hydrocephalus; inph patients; shunt ... See more keywords
Abnormal cortical thickening and thinning in idiopathic normal-pressure hydrocephalus
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DOI: 10.1038/s41598-020-78067-x
Abstract: We investigated differences in cortical thickness between idiopathic normal-pressure hydrocephalus (INPH) patients and healthy controls. We also explored whether a relationship exists between cortical thinning and gait disturbance in INPH patients. Forty-nine INPH patients and… read more here.
Keywords: cortical thickening; idiopathic normal; inph patients; normal pressure ... See more keywords
Cerebrospinal Fluid Shunting Improves Long-Term Quality of Life in Idiopathic Normal Pressure Hydrocephalus.
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DOI: 10.1093/neuros/nyz297
Abstract: BACKGROUND The short- and long-term impact of cerebrospinal fluid shunting on quality of life (QoL) in idiopathic normal pressure hydrocephalus (INPH) is poorly understood. OBJECTIVE To investigate QoL in shunted INPH patients compared to the… read more here.
Keywords: inph; long term; inph patients; fluid shunting ... See more keywords
Elevated CSF inflammatory markers in patients with idiopathic normal pressure hydrocephalus do not promote NKCC1 hyperactivity in rat choroid plexus
Sign Up to like & getrecommendations! Published in 2021 at "Fluids and Barriers of the CNS"
DOI: 10.1186/s12987-021-00289-6
Abstract: Background Idiopathic normal pressure hydrocephalus (iNPH) is a potentially reversible neurological condition of unresolved etiology characterized by a clinical triad of symptoms; gait disturbances, urinary incontinence, and cognitive deterioration. In the present study, we aimed… read more here.
Keywords: csf; inflammatory markers; inph patients; choroid plexus ... See more keywords