Articles with "inpp5e ciliary" as a keyword



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Multiple ciliary localization signals control INPP5E ciliary targeting

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Published in 2022 at "eLife"

DOI: 10.1101/2022.01.25.477585

Abstract: Primary cilia are sensory membrane protrusions whose dysfunction causes diseases named ciliopathies. INPP5E is a ciliary phosphoinositide phosphatase mutated in ciliopathies like Joubert syndrome. INPP5E regulates numerous ciliary functions, such as cilium stability, trafficking, signaling,… read more here.

Keywords: ciliary localization; inpp5e ciliary; ciliary targeting; localization signals ... See more keywords