Simplified Protocol for Whole Body Patlak Parametric Imaging with 18 F-FDG PET/CT: Feasibility and Error Analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Medical physics"
DOI: 10.1002/mp.14187
Abstract: PURPOSE Parametric imaging using the Patlak model has been shown to provide improved lesion detectability and specificity. The Patlak model requires both tissue time-activity-curves (TACs) after equilibrium and knowledge of the input function from the… read more here.
Keywords: function; input function; population based; based input ... See more keywords
Simulation of a novel, non-invasive radiation detector to measure the arterial input function for dynamic PET.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.16055
Abstract: BACKGROUND Dynamic positron emission tomography (dPET) is a nuclear medicine imaging technique providing functional images for organs of interest with applications in oncology, cardiology, and drug discovery. This technique requires the acquisition of the time-course… read more here.
Keywords: input function; arterial input; analysis chain; detector ... See more keywords
Input function and modeling for determining bone metabolic flux using [18 F] sodium fluoride PET imaging: a step-by-step guide.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.16125
Abstract: Studies of skeletal metabolism using measurements of bone metabolic flux (Ki ) obtained with [18 F] sodium fluoride ([18 F]NaF) positron emission tomography (PET) scans have been used in clinical research for the last 30… read more here.
Keywords: bone; pet; input function; metabolic flux ... See more keywords
Quantitative 3D myocardial perfusion with an efficient arterial input function
Sign Up to like & getrecommendations! Published in 2019 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.28050
Abstract: The purpose of this study was to further develop and combine several innovative sequence designs to achieve quantitative 3D myocardial perfusion. These developments include an optimized 3D stack‐of‐stars readout (150 ms per beat), efficient acquisition… read more here.
Keywords: quantitative myocardial; perfusion; myocardial perfusion; input function ... See more keywords
Estimation of the capillary level input function for dynamic contrast‐enhanced MRI of the breast using a deep learning approach
Sign Up to like & getrecommendations! Published in 2022 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.29148
Abstract: To develop a deep learning approach to estimate the local capillary‐level input function (CIF) for pharmacokinetic model analysis of DCE‐MRI. read more here.
Keywords: capillary level; level input; deep learning; learning approach ... See more keywords
Optimization and impact of sensitivity mode on abbreviated scan protocols with population-based input function for parametric imaging of [18F]-FDG for a long axial FOV PET scanner
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-024-06745-3
Abstract: The long axial field of view, combined with the high sensitivity of the Biograph Vision Quadra PET/CT scanner enables the precise deviation of an image derived input function (IDIF) required for parametric imaging. Traditionally, this… read more here.
Keywords: patlak; mode; 18f fdg; uhs mode ... See more keywords
Modification of population based arterial input function to incorporate individual variation.
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DOI: 10.1016/j.mri.2017.09.010
Abstract: This technical note describes how to modify a population-based arterial input function to incorporate variation among the individuals. In DCE-MRI, an arterial input function (AIF) is often distorted by pulsated inflow effect and noise. A… read more here.
Keywords: variation; individual variation; population based; input function ... See more keywords
Sampling arterial input function (AIF) from peripheral arteries: Comparison of a temporospatial-feature based method against conventional manual method.
Sign Up to like & getrecommendations! Published in 2019 at "Magnetic resonance imaging"
DOI: 10.1016/j.mri.2018.11.017
Abstract: It is often difficult to accurately localize small arteries in images of peripheral organs, and even more so with vascular abnormality vasculatures, including collateral arteries, in peripheral artery disease (PAD). This poses a challenge for… read more here.
Keywords: function aif; method; sampling arterial; peripheral arteries ... See more keywords
Validation of a combined image derived input function and venous sampling approach for the quantification of [18F]GE-179 PET binding in the brain
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DOI: 10.1016/j.neuroimage.2021.118194
Abstract: Blood-based kinetic analysis of PET data relies on an accurate estimate of the arterial plasma input function (PIF). An alternative to invasive measurements from arterial sampling is an image-derived input function (IDIF). However, an IDIF… read more here.
Keywords: input function; pwb ratio; blood; idif venous ... See more keywords
Non-Invasive Quantification of the Brain [¹⁸F]FDG-PET Using Inferred Blood Input Function Learned From Total-Body Data With Physical Constraint
Sign Up to like & getrecommendations! Published in 2024 at "IEEE Transactions on Medical Imaging"
DOI: 10.1109/tmi.2024.3368431
Abstract: Full quantification of brain PET requires the blood input function (IF), which is traditionally achieved through an invasive and time-consuming arterial catheter procedure, making it unfeasible for clinical routine. This study presents a deep learning… read more here.
Keywords: pet; input function; brain; quantification ... See more keywords
Development of quantitative PET/MR imaging for measurements of hepatic portal vein input function: a phantom study
Sign Up to like & getrecommendations! Published in 2024 at "EJNMMI Physics"
DOI: 10.1186/s40658-024-00694-4
Abstract: Accurate pharmacokinetic modelling in PET necessitates measurements of an input function, which ideally is acquired non-invasively from image data. For hepatic pharmacokinetic modelling two input functions need to be considered, to account for the blood… read more here.
Keywords: pet; input function; portal vein;