LAUSR

An INS‐1 832/13 𝛽‐Cell Proteome Highlights the Rapid Regulation of Fatty Acid Biosynthesis in Glucose‐Stimulated Insulin Secretion

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0 Published in 2025 at "Proteomics"

DOI: 10.1002/pmic.70005

Abstract: Pancreatic beta cells secrete insulin in response to rising glucose levels, a process known as glucose‐stimulated insulin secretion (GSIS). Here, we acquire proteomes of rat pancreatic INS‐1 832/13 beta cells that were short‐term stimulated with… read more here.

Keywords: stimulated insulin; secretion; ins 832; glucose stimulated ... See more keywords

The Proliferative and Functional Roles of CEBP/A in Ins-1 832/13 Cells and Primary Rat Islets

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2 Published in 2023 at "Physiology"

DOI: 10.1152/physiol.2023.38.s1.5733656

Abstract: The beta cell transcription factor Nkx6.1, when overexpressed in primary rodent and human islets, is sufficient to enhance beta cell proliferation, increase insulin secretion and enhance cell survival. We have sought to define the transcriptional… read more here.

Keywords: cell; primary rat; 832 cells; ins 832 ... See more keywords

1830-P: Elucidating the Role of Reactive Metabolic By-Products as Predictors and Drivers of Type 2 Diabetes

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0 Published in 2025 at "Diabetes"

DOI: 10.2337/db25-1830-p

Abstract: Introduction and Objective: More than 35% of the US population over the age of 18 has pre-diabetes, the precursor to overt type 2 diabetes (T2D). The mechanisms by which individuals progress from pre-diabetes to T2D… read more here.

Keywords: role; pre diabetes; none; type diabetes ... See more keywords