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Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2018.10.020
Abstract: Elamipretide is a tetrapeptide that restores defects in mitochondrial function, binds to cardiolipin, and is being tested in clinical trials for mitochondria-related diseases. However, whether elamipretide modulates mitochondrial quality control and dynamics, processes essential to…
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Keywords:
mitophagosome formation;
ins1 cells;
cells elamipretide;
nutrient excess ... See more keywords
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Published in 2019 at "Diabetes"
DOI: 10.2337/db19-2189-p
Abstract: Background: Programmed death-ligand 1 (PD-L1) plays a critical role to protect β-cells against immune attack. Interferon regulatory factor 1 (IRF1) is a key transcriptional factor to regulate PD-L1 expression, which is induced by various cytokines…
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Keywords:
expression;
none;
human iapp;
hiapp ... See more keywords