Articles with "insertion mutation" as a keyword



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Non-small cell lung cancer with EGFR exon 20 insertion mutation: a systematic literature review and meta-analysis of patient outcomes

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Published in 2022 at "Current Medical Research and Opinion"

DOI: 10.1080/03007995.2022.2083326

Abstract: Abstract Introduction EGFR exon 20 insertion mutation-positive non-small cell lung cancer (NSCLC) is rare, has a poor prognosis, and outcomes are not fully established. We describe and evaluate outcomes from real-world and clinical evidence in… read more here.

Keywords: exon insertion; insertion; insertion mutation; egfr exon ... See more keywords
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Targeting EGFR Exon 20 Insertion Mutation in Non–small cell Lung Cancer: Amivantamab and Mobocertinib

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Published in 2022 at "Annals of Pharmacotherapy"

DOI: 10.1177/10600280221098398

Abstract: Objective To evaluate clinical data regarding the use of amivantamab and mobocertinib for epidermal growth factor receptor (EGFR) exon 20 insertion mutation non–small cell lung cancer (NSCLC) and assess their potential impact on the care… read more here.

Keywords: exon insertion; egfr exon; insertion mutation; amivantamab mobocertinib ... See more keywords