Rationally Engineering a pH-Low Insertion Peptide Variant Probe for High-Sensitivity Imaging of Early Tumors.
Sign Up to like & getrecommendations! Published in 2025 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.5c04650
Abstract: The detection of early stage tumors is essential in oncology but remains a formidable challenge. Here, we developed a fluorescent pH low insertion peptide (pHLIP) variant probe, 4 M pHLIP-Cy5.5, that can recognize the weak… read more here.
Keywords: phlip cy5; low insertion; sensitivity; phlip ... See more keywords
Decoration of Nanovesicles with pH (Low) Insertion Peptide (pHLIP) for Targeted Delivery
Sign Up to like & getrecommendations! Published in 2018 at "Nanoscale Research Letters"
DOI: 10.1186/s11671-018-2807-8
Abstract: Acidity at surface of cancer cells is a hallmark of tumor microenvironments, which does not depend on tumor perfusion, thus it may serve as a general biomarker for targeting tumor cells. We used the pH… read more here.
Keywords: low insertion; peptide phlip; phlip; insertion peptide ... See more keywords