Insertion Sequences Disrupting mgrB in Carbapenem-Resistant Klebsiella pneumoniae Strains in Brazil.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2020.11.003
Abstract: OBJECTIVES This study aimed to characterize insertional mutations disturbing mgrB in carbapenem-resistant K. pneumoniae (CRKp). METHODS One hundred eighteen clinical CRKp strains were surveyed for polymyxin resistance and insertion sequences (IS) disrupting mgrB. RESULTS Seventy-eight… read more here.
Keywords: sequences disrupting; insertion; mgrb; mgrb carbapenem ... See more keywords
Experimental demonstration of operon formation catalyzed by insertion sequence
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DOI: 10.1093/nar/gkac004
Abstract: Abstract Operons are a hallmark of the genomic and regulatory architecture of prokaryotes. However, the mechanism by which two genes placed far apart gradually come close and form operons remains to be elucidated. Here, we… read more here.
Keywords: insertion sequences; insertion; insertion sequence; operon formation ... See more keywords
Insertion sequences drive the emergence of a highly adapted human pathogen
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DOI: 10.1099/mgen.0.000265
Abstract: Pseudomonas aeruginosa is a highly adaptive opportunistic pathogen that can have serious health consequences in patients with lung disorders. Taxonomic outliers of P. aeruginosa of environmental origin have recently emerged as infectious for humans. Here,… read more here.
Keywords: drive emergence; sequences drive; pathogen; insertion ... See more keywords
Insertion sequences and other mobile elements associated with antibiotic resistance genes in Enterococcus isolates from an inpatient with prolonged bacteraemia
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DOI: 10.1099/mgen.0.000855
Abstract: Insertion sequences (ISs) and other transposable elements are associated with the mobilization of antibiotic resistance determinants and the modulation of pathogenic characteristics. In this work, we aimed to investigate the association between ISs and antibiotic… read more here.
Keywords: antibiotic resistance; elements associated; insertion sequences; inpatient prolonged ... See more keywords
Palidis: fast discovery of novel insertion sequences
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DOI: 10.1099/mgen.0.000917
Abstract: The diversity of microbial insertion sequences, crucial mobile genetic elements in generating diversity in microbial genomes, needs to be better represented in current microbial databases. Identification of these sequences in microbiome communities presents some significant… read more here.
Keywords: catalogue; insertion sequences; palidis; insertion ... See more keywords
Insertion sequences related to ISAjo2 target pdif and dif sites and belong to a new IS family, the IS1202 family
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DOI: 10.1099/mgen.0.000953
Abstract: Several insertion sequences (IS) found in various Acinetobacter species exhibit target specificity. They are found, in the same orientation, 5 bp from the XerC binding site of the pdif sites associated with dif modules in Acinetobacter… read more here.
Keywords: family; insertion sequences; is1202 family; dif sites ... See more keywords
Genome Plasticity by Insertion Sequences Learned From a Case of Radiation-Resistant Bacterium Deinococcus geothermalis
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DOI: 10.1177/11779322211037437
Abstract: The genome of the radiation-resistant bacterium Deinococcus geothermalis contains 19 types of insertion sequences (ISs), including 93 total transposases (Tpases) in 73 full-length ISs from the main chromosome and 2 mega plasmids. In this study,… read more here.
Keywords: deinococcus; bacterium deinococcus; insertion sequences; resistant bacterium ... See more keywords
Beyond to the Stable: Role of the Insertion Sequences as Epidemiological Descriptors in Corynebacterium striatum
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.806576
Abstract: In recent years, epidemiological studies of infectious agents have focused mainly on the pathogen and stable components of its genome. The use of these stable components makes it possible to know the evolutionary or epidemiological… read more here.
Keywords: insertion sequences; beyond stable; insertion; corynebacterium striatum ... See more keywords
The Impact of Insertion Sequences on O-Serotype Phenotype and Its O-Locus-Based Prediction in Klebsiella pneumoniae O2 and O1
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DOI: 10.3390/ijms21186572
Abstract: Klebsiella pneumoniae is a nosocomial pathogen, pointed out by the World Helth Organisation (WHO) as “critical” regarding the highly limited options of treatment. Lipopolysaccharide (LPS, O-antigen) and capsular polysaccharide (K-antigen) are its virulence factors and… read more here.
Keywords: phenotype; antigen; insertion sequences; locus ... See more keywords