Articles with "insertion transgenes" as a keyword



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Fluorescence-assisted sequential insertion of transgenes (FASIT): an approach for increasing specific productivity in mammalian cells

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-69709-1

Abstract: Currently, the generation of cell lines for the production of recombinant proteins has the limitation of unstable gene expression due to the repeat-induced gene silencing or the loss of transgene copies resulting from recombination events.… read more here.

Keywords: expression; sequential insertion; insertion transgenes; gene ... See more keywords