Alu insertion variants alter mRNA splicing
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1086
Abstract: Abstract RNA splicing is a highly regulated process dependent on sequences near splice sites. Insertions of Alu retrotransposons can disrupt splice sites or bind splicing regulators. We hypothesized that some common inherited polymorphic Alu insertions… read more here.
Keywords: variants alter; alu; alter mrna; insertion variants ... See more keywords
Alu insertion variants alter gene transcript levels.
Sign Up to like & getrecommendations! Published in 2021 at "Genome research"
DOI: 10.1101/gr.261305.120
Abstract: Alu are high copy number interspersed repeats that have accumulated near genes during primate and human evolution. They are a pervasive source of structural variation in modern humans. Impacts that Alu insertions may have on… read more here.
Keywords: insertion; transcript levels; insertion variants; gene ... See more keywords