Articles with "insertional activation" as a keyword



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HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells

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Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-00609-1

Abstract: HIV-1 insertions targeting BACH2 or MLK2 are enriched and persist for decades in hematopoietic cells from patients under combination antiretroviral therapy. However, it is unclear how these insertions provide such selective advantage to infected cell… read more here.

Keywords: bach2; stat5b; regulatory cells; mediated insertional ... See more keywords