Inside-Out Design of Zinc-Binding Proteins with Non-Native Backbones.
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DOI: 10.1021/acs.biochem.2c00595
Abstract: The de novo design of functional proteins requires specification of tertiary structure and incorporation of molecular binding sites. Here, we develop an inside-out design strategy in the molecular modeling program Rosetta that begins with amino… read more here.
Keywords: inside design; zinc; design; binding proteins ... See more keywords