Signaling Mechanisms of Myofibroblastic Activation: Outside-in and Inside-Out
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000493217
Abstract: Myofibroblasts are central mediators of fibrosis. Typically derived from resident fibroblasts, myofibroblasts represent a heterogeneous population of cells that are principally defined by acquired contractile function and high synthetic ability to produce extracellular matrix (ECM).… read more here.
Keywords: myofibroblastic activation; signaling mechanisms; inside signaling; activation ... See more keywords
FcαRI Dynamics Are Regulated by GSK-3 and PKCζ During Cytokine Mediated Inside-Out Signaling
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DOI: 10.3389/fimmu.2018.03191
Abstract: IgA binding to FcαRI (CD89) is rapidly enhanced by cytokine induced inside-out signaling. Dephosphorylation of serine 263 in the intracellular tail of FcαRI by PP2A and PI3K activation are instrumental in this process. To further… read more here.
Keywords: cytokine; dynamics regulated; gsk pkc; inside signaling ... See more keywords